Catalogue Number:A524905
Chemical Name:A524905
Synonyms:NHS[1,10-Dihydro-2,2,10,10-tetramethyl-4,8-bis(sulfomethyl)-2H-pyrano[3,2-g:5,6-g’]diquinolin-6-yl]benzenedicarboxylate-N-ethyl-N-(1-methylethyl)-2-propanamine; 5-(((2,5-Dioxopyrrolidin-1-yl)oxy)carbonyl)-2-(2,2,10,10-tetramethyl-4,8-bis(sulfomethyl)-1,10-dihydro-2H-pyrano[3,2-g:5,6-g’]diquinolin-6-yl)benzoic Acid
CAS Number:878549-45-2
Alternate CAS #
247145-38-6
Molecular Formula:C₃₇H₃₃N₃O₁₃S₂
Molecular Weight:791.8
Category:Research Tools; Molecular Biology; Fluorescent Reagents;
Applications:6-[2-Carboxy-4(or 5)-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]phenyl]-1,2,10,11-tetrahydro-2,2,10,10-tetramethyl-4,8-bis(sulfomethyl)-pyrano[3,2-g:5,6-g′]diquinolin-13-ium inner salt compd. with N-ethyl-N-(1-methylethyl)-2-propanamine is a related compound of CAS# 247145-38-6, which is a new fluorescent dye that is more fluorescdent and more photostable than its commonly used spectral analog. The dyes are insensitive to pH in the 4-10 range. compound of CAS# 247145-38-6 can be used in terbium-based time-gated Forster resonance energy transfer imaging for evaluating protein-protein interactions on cell membranes and gain insight into drug loading and permeability.
References:Panchuck-Voloshina, N., et al.: J. Histochem. Cytochem., 47, 1179 (1999); Linden, S., et al.: Dalton Trans., 44, 4994 (2015); Marguet, M., et al.: Angew. Chem., Int. Ed., 51, 1173 (2012); Ghosh, S., et al.: ACS Appl. Mater. Interfaces, 8, 30824 (2016)
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