(10β, 8β)-Dihydroxy Naltrexone

Chemical Name:(10β, 8β)-Dihydroxy Naltrexone
Synonyms:(4R,4aS,5S,7aR,12bS,13R)-3-(Cyclopropylmethyl)-4a,5,9,13-tetrahydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one
Molecular Formula:C₂₀H₂₃NO₆
Molecular Weight:373.4
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(10β, 8β)-Dihydroxy Naltrexone is a derivative of Naltrexone (N285750), a nonselective opioid receptor antagonist; congener of Naloxone.
References:Maickel, R.P., et al.: Ann. N.Y. Acad. Sci., 281, 321 (1976), Gritz, E.R., et al.: Clin. Pharmacol. Ther. 19, 773 (1976), Gonzales, J.P., et al.: Drugs, 35, 192 (1988), Berg, B.J., et al.: Drug Saf., 15, 274 (1996),
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