Chemical Name:N-Desacetyl-N-formyl Apremilast
Synonyms:N-[2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-formamide;
CAS Number:2077897-94-8
Molecular Formula:C₂₁H₂₂N₂O₇S
Appearance:White to Off-White Solid
Melting Point:147 – 151°C
Molecular Weight:446.47
Storage:-20°C
Solubility:Chloroform (Sparingly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Desacetyl-N-formyl Apremilast is the impurity of Apremilast (A729700), which is an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis.
References:Gan, E., et al.: BioDrugs, 27, 359 (2013); Pathan, E., et al.: Annal. Rheum. DIs., 72, 1475 (2013); Xiong, K., et al.: Anal. Methods, 8, 1889 (2016);
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