Chemical Name:N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-((4-fluorophenyl)sulfonyl)-3-hydroxy-2-methylpropanamide
Synonyms:Bicalutamide EP Impurity H
Molecular Formula:C₁₈H₁₄F₄N₂O₄S
Molecular Weight:430.37
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-((4-fluorophenyl)sulfonyl)-3-hydroxy-2-methylpropanamide is an impurity of Bicalutamide (B382000); a non-steroidal peripherally active antiandrogen. Also used as an antineoplastic (hormonal).
References:Tucker, H., et al.: J. Med. Chem., 31, 954 (1988); Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990); Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993); McKillop, D., et al.: Xenobiotica, 25, 623 (1995)
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