Chemical Name:N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-((4-fluorophenyl)sulfonyl)-3-hydroxy-2-methylpropanamide-d4
Synonyms:Bicalutamide EP Impurity H-d4
Molecular Formula:C₁₈H₁₀D₄F₄N₂O₄S
Molecular Weight:434.4
Category:Standards; Isotopic Labeled Analogues;
Applications:N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-((4-fluorophenyl)sulfonyl)-3-hydroxy-2-methylpropanamide-d4 is the isotope labelled analog of N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-((4-fluorophenyl)sulfonyl)-3-hydroxy-2-methylpropanamide (C987435); an impurity of Bicalutamide (B382000) which is a non-steroidal peripherally active antiandrogen. Also used as an antineoplastic (hormonal).
References:Tucker, H., et al.: J. Med. Chem., 31, 954 (1988); Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990); Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993); McKillop, D., et al.: Xenobiotica, 25, 623 (1995)
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