N’-[2-[2,4-Dimethylphenyl)thio]phenyl] Vortioxetine-d8

Chemical Name:N’-[2-[2,4-Dimethylphenyl)thio]phenyl] Vortioxetine-d8
Synonyms:N,N’-bis[2-[(2,4-Dimethylphenyl)thio]phenyl]-piperazine-d8
Alternate CAS #:Unlabelled CAS# N/A
Molecular Formula:C₃₂H₂₆D₈N₂S₂
Molecular Weight:518.81
Category:Building Blocks; Isotopic Labeled Analogues;
Applications:N’-[2-[2,4-Dimethylphenyl)thio]phenyl] Vortioxetine-d8 is labelled N’-[2-[2,4-Dimethylphenyl)thio]phenyl] Vortioxetine (D477790), an impurity of Vortioxetine (V766000, HBr salt) which is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.
References:Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)
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