Chemical Name:Linagliptin Methyldimer-d6
Synonyms:8-[(3R)-3-Amino-1-piperidinyl]-1-[[4-[[2-[[8-[(3R)-3-amino-1-piperidinyl]-7-(2-butyn-1-yl-d3)-2,3,6,7-tetrahydro-3-methyl-2,6-dioxo-1H-purin-1-yl]methyl]-1,4-dihydro-4-methyl-4-quinazolinyl]methyl]-2-quinazolinyl]methyl]-7-(2-butyn-1-yl-d3)-3,7-dihydro-3-methyl-1H-purine-2,6-dione; 8-((R)-3-Aminopiperidin-1-yl)-1-((4-((2-((8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl-d3)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl)-4-methyl-1,4-dihydroquinazolin-4-yl)methyl)quinazolin-2-yl)methyl)-7-(but-2-yn-1-yl-d3)-3-methyl-1H-purine-2,6(3H,7H)-dione
Alternate CAS #:Unlabelled: 1418133-47-7
Molecular Formula:C₅₀H₅₀D₆N₁₆O₄
Molecular Weight:951.12
Category:Building Blocks; Isotopic Labeled Analogues;
Applications:Linagliptin Methyldimer-d6 is a labeled analogue of Linagliptin Dimer (L465910), which inhibits dipeptidylpeptidase-IV (DPP-IV) and may be used in the treatment of type 2 diabetes.
References:Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);
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