Chemical Name:Lapatinib-d7 Ditosylate
Synonyms:N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl-d7]amino]methyl]-2-furanyl]-4-quinazolinamine Bis(4-methylbenzenesulfonate) Ditosylate; GW-572016F-d7 Ditosylate; Tykerb-d7 Ditosylate;
CAS Number:1009307-24-7
Alternate CAS #:388082-77-7-unlabelled
Molecular Formula:C₄₃H₃₅D₇ClFN₄O₁₀S₃
Molecular Weight:932.5
Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Labelled Lapatinib (L175800). Reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic.
References:Kim, T.E., et al.: Drugs, 6, 886 (2003), Wood, E.R., et al.: Cancer Res., 64, 6652 (2004), Spector, N.L., et al.: J. Clin. Oncol., 23, 2502 (2005),
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