Chemical Name:KRP-203-d5
Synonyms:2-Amino-2-(2-chloro-4-((3-((phenyl-d5)methoxy)phenyl)thio)phenethyl)propane-1,3-diol;
Alternate CAS #:509088-69-1
Molecular Formula:C₂₄H₂₁D₅ClNO₃S
Molecular Weight:449.02
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:KRP-203-d5 is a labelled analogue of KRP-203 (K660300), which is a novel sphingosine-1-phosphate receptor agonists in the treatment of autoimmune diseases. Immunosuppressant.
References:Yanagawa, Y., et al.: J. Immunol., 160, 5493 (1998), Takahashi, M., et al.: Cardiovasc. Res., 52, 438 (2001), Liu, G., et al.: J. Med. Chem., 43, 4025 (2000), Shimizu, H., et al.: Circulation, 111, 222 (2005);
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