Chemical Name:isopropyl (4-(2-(5-Methylpyrazine-2-carboxamido)ethyl)phenyl)sulfonylcarbamate
Synonyms:Glipizide N(sulfonamide)-Isopropyl Carbamate;
Molecular Formula:C₁₈H₂₂N₄O₅S
Appearance:White to Off-White Solid
Melting Point:>160°C
Molecular Weight:406.46
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:isopropyl (4-(2-(5-Methylpyrazine-2-carboxamido)ethyl)phenyl)sulfonylcarbamate is an impurity of Glipizide (G410225), a sulfonylurea hypoglycemic agent. Used as an antidiabetic.
References:Ambrogi, et al.: Arzneimittel-Forsch., 21, 200 (1971), Fuccella, et al.: J. Clin. Pharmacol., 13, 68 (1973), Brogden, R.N., et al.: Drugs, 18, 329 (1979), Lebovitz, H.E., et al.: Pharmacother., 5, 63 (1985)
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