Chemical Name:Ioticasone Furoate
Synonyms:6α,9-Difluoro-11β-hydroxy-16α-methyl-17-((iodosulfanyl)carbonyl)-3-oxo-androsta-1,4-diene-17a-yl Furoate
Molecular Formula:C₂₇H₂₉F₂IO₆S
Appearance:White to Off-White Solid
Molecular Weight:646.48
Storage:-20°C, Inert atmosphere
Solubility:Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Very Slightly)
Category:Standards; Chiral Molecules; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Ioticasone Furoate is derived from 6α,9α-Difluoro-11β,17α-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17a-carbothioic Acid (D445755), which is an intermediate in the synthesis of fluticasone propionate and fluticasone propionate impurity.
References:Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990), Mitchison, H.C., et al. : Gut, 32 260 (1991), Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)
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