Chemical Name:Hydroxy Cariprazine
Synonyms:N’-[trans-4-[2-[4-(2,3-dichloro-4-hydroxyphenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethyl-Urea
CAS Number:1084891-95-1
Molecular Formula:C₂₁H₃₂Cl₂N₄O₂
Molecular Weight:443.41
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Hydroxy cariprazine is a derivative of cariprazine (C183490), an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.
References:(1) Gruender, G.: Curr. Opin. Invest. Drugs, 11, 823 (2010); (2) Seneca, N. et al.: Psychopharmacology, 218, 579 (2011); (3) Kiss, B. et al.: J. Pharmacol. Exp. Therap., 333, 328 (2010).
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