Chemical Name:Giripladib
Synonyms:4-[3-[5-Chloro-1-(diphenylmethyl)-2-[2-[[[[2-(trifluoromethyl)phenyl]methyl]sulfonyl]amino]ethyl]-1H-indol-3-yl]propyl]benzoic Acid; 4-(3-[5-Chloro-1-(diphenylmethyl)-2-[2-(((2-(trifluoromethyl)benzyl)sulfonyl)amino)ethyl]-1H-indole-3-yl]propyl)benzoic Acid; PLA 695
CAS Number:865200-20-0
Molecular Formula:C₄₁H₃₆ClF₃N₂O₄S
Molecular Weight:745.25
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Giripladib inhibits cytosolic phospholipase A2 (cPLA2) which in turn radiosensitizes tumors in lung cancer animal models.
References:Thotala, D., et al.: PLoS One, 8, e69688 (2013)
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