Chemical Name:Florfenicol Dimer Impurity
Synonyms:2,2-Dichloro-N-[(1R,2R)-1-[[[(1R,2S)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]amino]methyl]-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide;
Alternate CAS #:1217739-31-5 (relative stereo)
Molecular Formula:C₂₂H₂₇Cl₂FN₂O₇S₂
Molecular Weight:585.49
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:An impurity of Florfenicol (F405750), a fluorinated derivative of thiamphenicol. Florfenicol inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. Florfenicol is used as an antibacterial.
References:Kim, E and Aoki, T.: Microbiol. Immunol., 40, 665, (1996), Keyes, K.: Antimicrob. Agents Chemother., 44, 421 (2000)
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