Chemical Name:EC 313
Synonyms:(11β,17β)-3′-(Difluoromethylene)-11-[4-(3-furanyl)phenyl]-4′,5′-dihydrospiro[estra-4,9-diene-17,2′(3’H)-furan]-3-one; 21,21-Difluoro-11β-[4′-(3′-furanyl)phenyl]17,23-epoxy-19,24-dinor-17α-chola-4,9,20-triene; (2’S,8S,11R,13S,14S)-3′-(Difluoromethylene)-11-(4-(furan-3-yl)phenyl)-13-methyl-1,2,4′,5′,7,8,11,12,13,14,15,16-dodecahydro-3’H-spiro[cyclopenta[a]phenanthrene-17,2′-furan]-3(6H)-one
CAS Number:1249398-29-5
Molecular Formula:C₃₂H₃₂F₂O₃
Molecular Weight:502.59
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:EC 313 is a tissue selective progesterone receptor (SPRM) that reduces growth and proliferation of uterine fibroids in human uterine fibroid tissue xenograft models.
References:Nair, H. B., et al.: Sci. Rep., 9, 1 (2019)
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