Chemical Name:Dihydro Folic Acid-D4 (Technical Grade)
Synonyms:N-[4-[[(2-Amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid-D4; N-[p-[[(2-Amino-7,8-dihydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-L- Ggutamic Acid-D4; N-[4-[[(2-Amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid-D4; 7,8-Dihydro-L-folic Acid-D4; 7,8-Dihydrofolic Acid-D4; Dihydrofolic Acid-D4;
Alternate CAS #:Unlabelled: 4033-27-6
Molecular Formula:C₁₉H₁₇D₄N₇O₆
Molecular Weight:447.44
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Dihydro Folic Acid-D4 is an isotopic analog of Dihydro Folic Acid (D449700), an intermediate in mammalian conversion of dietary folic acid to tetrahydrofolate by dihydrofolate reductase (DHFR).
References:Andres, J., et al.: Bioorg. Chem., 24, 10 (1996); Benkovic, S., et al.: Science, 301, 1196 (2003); Williams, D; J Mol Biol 2003, 329, 389,,,Krahn, J., et al.: Biochemistry, 46, 14878 (2007);
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