Chemical Name:Di-desfluoro Ezetimibe
Synonyms:(3R,4S)-4-(4-Hydroxyphenyl)-3-[(3S)-3-hydroxy-3-phenylpropyl]-1-phenyl-2-azetidinone;
CAS Number:1251741-03-3
Molecular Formula:C₂₄H₂₃NO₃
Molecular Weight:373.44
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Di-desfluoro Ezetimibe is a dehalogenated impurities observed in halogen-containing pharmaceuticals. Also, it is a related compound to Ezetimibe (E975000), which is an antihyperlipoproteinemic. A cholesterol absorption inhibitor.
References:Regalado, E. L., et al.: J. Pharm. Biomed. Anal. 92, 1-5 (2014); van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000);
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