Chemical Name:D-erythro-Dihydrosphingosine-1-phosphate
Synonyms:DL-erythro-2-Amino-1,3-Octadecanediol 1-(Dihydrogen Phosphate);DL-erythro-Sphinganine-1-phosphate;
CAS Number:28508-07-8
Molecular Formula:C₁₈H₄₀NO₅P
Molecular Weight:381.49
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Lipids/Fatty Acids, Glycerol Derivatives;
Applications:D-erythro-Dihydrosphingosine-1-phosphate is a saturated analog of D-erythro-Sphingosine-1-phosphate a putative lipid second messenger; found to inhibit cellular mobility of melanoma cells at very low concentrations with no toxic effects thereby making it a possible agent for prevention of tumor cell metastasis and inflammatory processes.
References:Yeh, C., et al.: Am. J. Physiol., 296, H1193 (2009), Hagen, N., et al.: J. Biol. Chem., 284, 11346 (2009), Kuehnel, M., et al.: J. Cell Sci., 122, 499 (2009),
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