CEV (R)-S-Oxide

Chemical Name:CEV (R)-S-Oxide
CAS Number:124751-37-7
Molecular Formula:C₁₀H₁₇NO₂S
Appearance:White to Off-White Solid
Melting Point:110-112°C
Molecular Weight:215.31
Storage:-20°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:CEV S-Oxide 2 is an impurity compound of Cevimeline (C283500). Cevimeline is a novel muscarinic M1 and M3 receptor agonist. Sialagogue.
References:Masunaga, H., et al.: Eur. J. Pharmacol., 339, 1 (1997), Arisawa, H., et al.: Arzneim.-Forsch., 52, 14 (2002), Yasuda, H., et al.: Clin. Drug Invest., 22, 67 (2002), Ono, M., et al.: Am. J. Ophthalmol., 138, 6 (2004),
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