Catalogue Number:A101055
Chemical Name:A 54556A (~90%)
Synonyms:(4R)-N-[(2E,4E,6E)-1-oxo-2,4,6-Octatrien-1-yl]-L-phenylalanyl-L-seryl-L-prolyl-N-methyl-L-alanyl-L-alanyl-4-methyl-L-proline (6→2)-lactone; A 54556 factor A; ADEP 1; Acyldepsipeptide 1; Acyldepsipeptide A; Antibiotic A 54556A
CAS Number:95398-45-1
Molecular Formula:C₃₈H₅₀N₆O₈
Appearance:Pale Yellow to Light Brown Solid
Melting Point:>180ºC (dec.)
Molecular Weight:718.84
Storage:4°C, Light sensitive, Light sensitive
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability
Light Sensitive
Category:Standards; Chiral Molecules; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
Applications:A 54556A is an antibiotic from streptomyces can inhibit the growth of 786-O, 769-P, and ACHN renal carcinoma cells in MTT assay. A 54556A may be a potential chemotherapeutic agent for treatment of renal carcinoma.
References:Goodreid, J.D., et. al: J. Nat. Prod., 77, 2170 (2014); Xu, S., et. al.: Biochem. Bioph. Res. Co., 438, 468 (2013)
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