Catalogue Number:B293795
Chemical Name:5-Bromo-6,7-demethylenedeoxypodophyllotoxin
Synonyms:(3aR,9R,9aR)-5-Bromo-6,7-dihydroxy-9-(3,4,5-trimethoxyphenyl)-3a,4,9,9a-tetrahydronaphtho[2,3-c]furan-1(3H)-one
CAS Number:93108-15-7
Molecular Formula:C₂₁H₂₁BrO₇
Molecular Weight:465.29
Storage:20°C
Solubility:Dichloromethane
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Natural Products;
Applications:5-Bromo-6,7-demethylenedeoxypodophyllotoxin is a derivative of 6,7-Demethylenedeoxypodophyllotoxin (D295560), a metabolite of 4-Deoxypodophyllotoxin (D249500). 4-Deoxypodophyllotoxin is a medicinal herb product isolated from Anthriscus sylvestris Hoffm. It is well known for its antitumor, antiviral, and anti-inflammatory activities. 4-Deoxypodophyllotoxin was also shown to inhibit the passive cutaneous anaphylaxis reaction.
References:Lin, C.X., et al.: Planta. Med., 70, 474 (2004); Peng, Xu., et al.: Neurotoxicol., 31, 680 (2010); Kim, Y., et al.: Planta, Med., 68, 271 (2002);
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