Catalogue Number:B366500
Chemical Name:BG45
Synonyms:N-(2-Aminophenyl)2-pyrazinecarboxamide;
CAS Number:926259-99-6
Molecular Formula:C₁₁H₁₀N₄O
Appearance:Light Yellow Solid
Melting Point:160-163°C
Molecular Weight:214.22
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:BG45 acts as an HDAC class I inhibitor with selectvity for HDAC3. HDACs represent novel targets for anti-tumer drugs treating various cancers including multiple myeloma cancer.
References:Minami, J. et al.: Leukemia, 28, 680 (2014); Pinder, J. et al.: Pinder, J. et al.: Tetrahedron. Lett., 55, 4853 (2014);
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