Catalogue Number:A112500
Chemical Name:ABT 263
Synonyms:4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide; Navitoclax
CAS Number:923564-51-6
Molecular Formula:C₄₇H₅₅ClF₃N₅O₆S₃
Appearance:White to Pale Brown Solid
Melting Point:>122°C (dec.)
Molecular Weight:974.61
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A novel inhibitor of antiapoptotic BCL-2 proteins
References:Adams, J., et al.: Science, 281, 1322 (1998),
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