Catalogue Number:B327990
Chemical Name:(R)-Betaxolol Hydrochloride
Synonyms:(2R)-1-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanolHydrochloride; (+)-Betaxolol Hydrochloride; (R)-(+)-Betaxolol Hydrochloride; Dextrobetaxolol Hydrochloride;
CAS Number:91878-54-5
Alternate CAS #
91878-53-4-free base
Molecular Formula:C₁₈H₃₀ClNO₃
Appearance:White to Off-White Solid
Melting Point:>105°C (dec.)
Molecular Weight:343.89
Storage:-20°C
Solubility:Chloroform (Slightly), Methanol (Slightly, Sonicated)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(R)-Betaxolol is the R-isomer of Betaxolol (B328000), a cardioselective b1-adrenergic blocker (1,2,3). It is also an antihypertensive and antiglaucoma agent (4).
References:(1) Bickel, M., et al.: J. Pharm. Pharmacol., 32, 669 (1980)
(2) Cadigan, P.J., et al.: Br. J. Clin. Pharmacol., 9, 569 (1980)
(3) Pathe, M., et al.: Therapie, 37, 75 (1982)
(4) Panchal, V. S., et al.: J. Pharm. Sci. Pharmacol. 2, 21 (2015)
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