Catalogue Number:B397925
Chemical Name:5-([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazole
Synonyms:4-([1,1′-Biphenyl]-4-ylphenylmethyl)1H-imidazole; Bifonazole EP Impurity B;
Impurity:Bifonazole EP Impurity B
CAS Number:91679-37-7
Molecular Formula:C₂₂H₁₈N₂
Appearance:White to Off-White Solid
Melting Point:>103C (dec.)
Molecular Weight:310.39
Storage:4°C, Light sensitive, Light sensitive
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability
Light sensitive
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-([1,1-Biphenyl]-4-ylphenylmethyl)-1H-Imidazole (Bifonazole EP Impurity B) is a compound derived from Bifonazole (B383400), an anti-fungal agent used in the treatment of skin diseases. Causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.
References:Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);
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