Catalogue Number:C989800
Chemical Name:Cyclopentenylcytosine
Synonyms:4-Amino-1-[(1R,4R,5S)-4,5-dihydroxy-3-(hydroxymethyl)-2-cyclopenten-1-yl]-2(1H)-pyrimidinone; [1R-(1α,4β,5β)]-4-Amino-1-[4,5-dihydroxy-3-(hydroxymethyl)-2-cyclopenten-1-yl]-2(1H)-pyrimidinone; CPEC; NSC 375575
CAS Number:90597-22-1
Molecular Formula:C₁₀H₁₃N₃O₄
Molecular Weight:239.23
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Cyclopentenylcytosine induces senescence in breast cancer cells through nucleolar stress response and activation of p53. It also has antitumor activity.
References:Huang, M., et al.: Mol. Pharmacol., 80, 40 (2011); Van Bree, C., et al.: Int. J. Oncol., 34, 813 (2009)
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