CAS:873225-46-8|[4-[(4-Benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone

Catalogue Number:B207020
Chemical Name:[4-[(4-Benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone
Synonyms:IKK-16
CAS Number:873225-46-8
Molecular Formula:C₂₈H₂₉N₅OS
Molecular Weight:483.63
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:[4-[(4-Benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone is a potential novel IκB kinase 2 (IKK2) inhibitor used in the treatment of various immune/inflammatory disorders.
References:Xie, H.Z., et al.: J. Biomole. Stru. Dyn., 29, 165 (2011); Waelchli, R., et al.: Bioorg. Med. Chem. Lett., 16, 108 (2006); Nagarajan, S., et al.: Bioorg. Med. Chem., 18, 3951 (2010);
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