Catalogue Number:B367000
Chemical Name:BGJ 398
Synonyms:3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea; Infigratinib; NVP-BGJ 398
CAS Number:872511-34-7
Molecular Formula:C₂₆H₃₁Cl₂N₇O₃
Appearance:White Solid
Melting Point:>211°C (dec.)
Molecular Weight:560.48
Storage:4°C
Solubility:DMSO (Slightly)
Category:Standards; Enzyme Activators and Inhibitors;
Applications:BGJ 398 is a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase.
References:Guagnano, V., et al.: J. Med. Chem., 54, 7066 (2011); Konecny, G., et al.: Mol. Cancer Ther., 12, 632 (2013)
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