CAS:710951-92-1|(11b,16b)-11,21-bis(acetyloxy)-2′-methyl-5’H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione(Deflazacort Impurity)

Catalogue Number:B400605
Chemical Name:(11b,16b)-11,21-bis(acetyloxy)-2′-methyl-5’H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione(Deflazacort Impurity)
Synonyms:Deflazacort Impurity C;
Impurity:Deflazacort Impurity C
CAS Number:710951-92-1
Molecular Formula:C₂₇H₃₃NO₇
Appearance:White to Off-White Solid
Melting Point:211-214°C
Molecular Weight:483.55
Storage:-20°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Research Tools; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(11b,16b)-11,21-bis(acetyloxy)-2′-methyl-5’H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, is an impurity of Deflazacort, which is a systemic corticosteroid, used for rheumatoid arthritis and lupus.
References:Nathansohn, G., et al.: J. Med. Chem., 10,799 (1967), Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984), Imbimbo, B., et al.: Adv. Exp. Med. Biol., 171, 241 (1984),
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