Catalogue Number:D281860
Chemical Name:Desacetyl Forskolin
Synonyms:(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-Ethenyldodecahydro-5,6,10,10b-tetrahydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one; 7-Deacetylforskolin; 7-Desacetylforskolin; 7-Deacetylcoleonol; Deacetylforskolin; Forskolin D;
CAS Number:64657-20-1
Molecular Formula:C₂₀H₃₂O₆
Appearance:White to Off-White Solid
Melting Point:171-173°C
Molecular Weight:368.46
Storage:4°C
Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Desacetyl Forskolin is an analogue of Forskolin (F701800). Desacetyl Forskolin was tested for its ability to activate rat brain adenylate cyclase, activate detergent-solubilized rat brain adenylate cyclase, increase cyclic AMP in intact S49 wild-type cells, and inhibit the binding of 3H-forskolin to rat brain membranes.
References:Desouza, N., et al.: Med. Res. Rev., 3, 201 (1983); Seamon, K., et al.: J. Med. Chem., 26, 436 (1983); Seguin, E., et al.: Planta Medica, 54, 4 (1988);
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