Catalogue Number:B194270
Chemical Name:Benzyl (2R)-2-Chlorocarbonylpyrrolidine-1-carboxylate
Synonyms:(R)-2-(Chlorocarbonyl)-1-pyrrolidinecarboxylic Acid Phenylmethyl Ester; N-(Benzyloxycarbonyl)-D-proline Chloride; N-Cbz-D-proline Chloride;
CAS Number:61350-62-7
Molecular Formula:C₁₃H₁₄ClNO₃
Molecular Weight:267.71
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Benzyl (2R)-2-Chlorocarbonylpyrrolidine-1-carboxylate is an intermediate used in the synthesis of 5-Ethyl-3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indole (E924900), which is an impurity of Eletriptan (E505000), a serotonin 5-HTIB/ID receptor agonist and an anti-migraine agent.
References:Madasu, S. B., et al.: Beilstein. J. Org. Chem., 8, 1400 (2012); Willems, E., et al.: Arch. Pharmacol., 358, 212 (1998), Napier, C., et al.: Eur. J. Pharmacol., 368, 259 (1999), Goadsby, P.J., et al.: Neurology, 54, 156 (2000)
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