Catalogue Number:B208405
Chemical Name:N-(2-Benzoyl-4-chlorophenyl)-2-chloro-N-methylacetamide
Synonyms:2′-Benzoyl-2,4′-dichloro-N-methylacetamide; 5-Chloro-2-(2-chloro-N-methylacetamido)benzophenone; N-Methyl-2′-benzoyl-2,4′-dichloroacetanilide; Diazepam EP Impurity B
Impurity:Diazepam EP Impurity B
CAS Number:6021-21-2
Molecular Formula:C₁₆H₁₃Cl₂NO₂
Appearance:White to Off-White Solid
Melting Point:121 – 123°C
Molecular Weight:322.19
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-(2-Benzoyl-4-chlorophenyl)-2-chloro-N-methylacetamide (Diazepam EP Impurity B) is the impurity of Temazepam (T017200), which is a pharmacologically active metabolite of Diazepam. It is used as a sedative and hypnotic drug.
References:Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981)
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