Catalogue Number:B324001
Chemical Name:Betahistine Dihydrochloride
Synonyms:N-Methyl-2-pyridineethanamine Dihydrochloride; 2-[2-(Methylamino)ethyl]pyridine Dihydrochloride; 2-[2-(Methylamino)ethyl]pyridine Dihydrochloride; Betaserc; PT 9; Serc; Sinmenier; Vasomotal;
CAS Number:5579-84-0
Alternate CAS #
HCl salt: 15430-48-5
Molecular Formula:C₈H₁₄Cl₂N₂
Appearance:White to Off-White Solid
Melting Point:148-155°C
Molecular Weight:209.12
Storage:-20°C
Solubility:Methanol (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Betahistine is most commonly used to treat the symptoms of Ménière’s disease and vertigo. Vasodilator.
References:Gilligan, P., et al.: J. Med. Chem., 43, 1641 (2000), Keller, P., et al.: Bioorg. Med. Chem., 8, 1213 (2000), Hauger, R., et al.: Pharmacol. Rev., 55, 21 (2003), Han, X., et al.: Bioorg. Med. Chem. Lett., 15, 3870 (2005),
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