Catalogue Number:A580085
Chemical Name:a-Aminoacetophenone (Mixed Salt, >85%)
Synonyms:2-Amino-1-phenylethanone; 2-Amino-1-phenyl-1-ethanone; 2-Amino-1-phenylethanone; 2-Aminoacetophenone; Phenacylamine; α-Aminoacetophenone
CAS Number:5468-37-1
Alternate CAS #
Free Amine: 613-89-8Hydrochloride:5468-37-1
Molecular Formula:C₈H₉NO • xHCl • xHBr
Appearance:Pale Brown to Light Brown Solid
Melting Point:189-191°C
Molecular Weight:135.17 + x(36.46) + x(80.91)
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Miscellaneous;
Applications:Mixed Salt of a-Aminoacetophenone, used in the preparation og pseudopeptidic inhibitors of human sirtuins1-3. This action effectually displays antiproliferative protperties in cancer cells. Also used in the preparation of dual δ/uopiod receptor agonists.
References:Mellini, P. et al.: J. Med. Chem., 56, 6681 (2013); Breslin, H. et al.: Bioorg. Med. Chem. Lett., 22, 4869 (2013);
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