Catalogue Number:B330250
Chemical Name:Betulinic Acid
Synonyms:Mairin; (+)-Betulinic acid; 3β-Hydroxylup-20(29)-en-28-oic Acid; Betulic Acid; Lupatic Acid; NSC 113090; β-Betulinic Acid; (3β)-3-HydroxyLup-20(29)-en-28-oic Acid;
CAS Number:472-15-1
Molecular Formula:C₃₀H₄₈O₃
Appearance:White to Pale Beige Solid
Melting Point:>235°C (dec.)
Molecular Weight:456.7
Storage:4°C
Solubility:DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Betulinic Acid is a natural pentacyclic triterpenoid. Betulinic Acid displays anti-inflammatory and anti-HIV activity. Betulinic Acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity
References:Pisha, E. et al.: Nat. Med., 1, 1046 (1995); Fulda, S. et al.: Cancer Res., 57, 4956 (1997); Kashiwada, Y. et al.: J. Med. Chem., 39, 1016 (1996); Genet, C. et al.: J. Med. Chem., 53, 178 (2010);
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