Catalogue Number:B287165
Chemical Name:1-(4-(Benzyloxy)-3-nitrophenyl)-2-bromoethanone
Synonyms:2-Bromo-1-[3-nitro-4-(phenylmethoxy)phenyl]Ethanone; 1-(Benzyloxy)-2-nitro-4-(2-bromoacetyl)benzene; 2-Bromo-1-(3-nitro-4-benzyloxyphenyl)ethanone; 2-Bromo-4′-Benzyloxy-3′-nitroacetophenone; 4′-(Benzyloxy)-2-bromo-3′-nitroacetophenone
CAS Number:43229-01-2
Molecular Formula:C₁₅H₁₂BrNO₄
Appearance:Off-White to Light Yellow Solid
Melting Point:137 – 138°C
Molecular Weight:350.16
Storage:-20°C
Solubility:Chloroform (Sparingly), Methanol (Slightly)
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:1-(4-(Benzyloxy)-3-nitrophenyl)-2-bromoethanone, can be used as an intermediate in the synthesis of Arformoterol Tartrate (A767505), which is a derivative of Arformoterol, a long acting beta-adrenoceptor agonist drug indicated for the treatment of chronic obstructive pulmonary disease (COPD).
References:Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993);
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