Catalogue Number:B387260
Chemical Name:Biochanin A-7-O-β-D-glucuronide
Synonyms:5,7-Dihydroxy-4’-methoxyisoflavone-7-O-β-D-glucuronide
CAS Number:38482-76-7
Molecular Formula:C₂₂H₂₀O₁₁
Molecular Weight:460.39
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Biochanin A-7-O-β-D-glucuronide is a metabolite of Biochanin A (B387250), an isoflavone with anticancer proliferation, differentiation and chemopreventitive properties. Acyl glucuronides have been linked with the toxic properties of drugs that contain carboxylic acid moieties. Multiple experiments have explored the potential biologic and toxicologic effects of acyl glucuronide metabolites of various drugs.
References:Chae, Y.H., et al.: Chem. Biol. Interactions, 82, 181 (1992), Jing, Y. and Waxman, S.: Anticancer Res., 15(4), 1147 (1995) Shipkova M., et al.: Ther. Drug. Monit., 25, 1 (2003); Regan, L., et al.: Biopharm. Drug. Dispos., 31, 367 (2010);
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