Catalogue Number:B386820
Chemical Name:Bimatoprost Acid
Synonyms:(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid; 17-Phenyl-18,19,20-trinor-PGF2α; PhXA 70; (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-5-heptenoic Acid; 17-Phenyl-18,19,20-trinorprostaglandin F2α; U 35687; [1R-[1α(Z),2β(1E,3S*),3α,5α]]-7-[3,5-Dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl]-5-heptenoic Acid;
CAS Number:38344-08-0
Molecular Formula:C₂₃H₃₂O₅
Appearance:White to Off-White Waxy Solid to Solid
Melting Point:82-84°C
Molecular Weight:388.5
Storage:-20°C, Inert atmosphere
Solubility:Dichloromethane (Slightly), DMSO (Sparingly), Methanol (Sparingly)
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Bimatoprost Acid is an impurity of the antiglaucoma agent Bimatoprost (B386820).Bimatoprost Acid is a metabolically stable analog of PGF2a (P838625) and is a potent agonist for the FP receptor.
References:Balapure, A.K. et al.: Biochem. Pharmacol., 38, 2375 (1989); Hellberg, M.R. et al.: J. Ocular Pharmacol. Ther., 19, 97 (2003); Krishna, P.M. et al.: J. Pharm. res., 4, 2381 (2011);
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