CAS:350797-57-8|1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-oxopropyl)-1H-Indole-7-carbonitrile

Catalogue Number:B288460
Chemical Name:1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-oxopropyl)-1H-Indole-7-carbonitrile
CAS Number:350797-57-8
Molecular Formula:C₂₂H₂₂N₂O₃
Molecular Weight:362.42
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:1-[3-(benzoyloxy)propyl]-2,3-dihydro-5-(2-oxopropyl)-1H-Indole-7-carbonitrile can be used to synthesize silodosin (S465005) which is a medication for treating the symptoms of benign prostatic hyperplasia. It can also be utilized by various ω-transaminases (ωTAs) to form silodosin amine intermediate.
References:Bhuta, S., et al.: Indian Pat. Appl. IN 2010MU02119 A 20140221 (2014); Simon, R. C., et al.: Tetrahedron: Asymmetry 25 284 (2014)
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