Catalogue Number:B285535
Chemical Name:Benzyl 5-Methoxy-2-methylindole-3-acetate
Synonyms:5-Methoxy-2-methyl-1H-indole-3-acetic Acid Phenylmethyl Ester; 5-Methoxy-2-methyl-Indole-3-acetic Acid Benzyl Ester
CAS Number:3285-40-3
Molecular Formula:C₁₉H₁₉NO₃
Molecular Weight:309.36
Category:Building Blocks;
Applications:Benzyl 5-Methoxy-2-methylindole-3-acetate is used in the synthesis of indomethacin analogues as nonsteroidal anti-inflammatory agents, that inhibit P-glycoprotein and/or MDR protein without COX-1/COX-2 inhibitory activity. As well used to synthesize indole-based prostaglandin D receptor antagonists.
References:Arisawa, M. et al.: J. MEd. Chem., 55, 8152 (2012); Scholz, M. et al.: Bioorg. Med. Chem., 20, 4830 (2012);
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