Catalogue Number:B375000
Chemical Name:BIBR 1532
Synonyms:2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-buten-1-yl]amino]-benzoic Acid
CAS Number:321674-73-1
Molecular Formula:C₂₁H₁₇NO₃
Appearance:White to Off-White Solid
Melting Point:>173ºC (dec.)
Molecular Weight:331.36
Storage:4°C, Light sensitive, Light sensitive
Solubility:DMSO (Slightly), Methanol (Slightly, Sonicated)
Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:BIBR 1532 is a mixed-type non-competitive inhibitor of telomerase. It specifically targets the telomerase reverse transcriptase catalytic subunit, TERT.
References:Damm, K., et al.: EMBO J., 20, 6958 (2001); Kelland, L.: Eur. J. Cancer, 41, 971 (2005); Pascolo, E., et al.: J. Biol. Chem., 277, 15566 (2002)
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