Catalogue Number:B197925
Chemical Name:Benznidazole
Synonyms:2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide; N-Benzyl-2-nitro-Imidazole-1-acetamide; Benznidazole; Benzonidazol; Benzonidazole; N-Benzyl-2-nitroimidazol-1-yl-acetamide; NSC 299972; Radanil; Ro 07-1051; Ro 71051; Rochagan;
CAS Number:22994-85-0
Molecular Formula:C₁₂H₁₂N₄O₃
Appearance:White to Off-White Solid
Melting Point:188-190°C
Molecular Weight:260.25
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Benznidazole (BNZ) is traditionally used to treat Chagas disease caused by Trypanosoma cruzi. The drugs used for the treatment of this disease, Nifurtimox and Benznidazole, are toxic and present severe side effects.
References:Abuin, G., et al.: Mol. Biochem. Parasitol ., 35, 229 (1989), Arora, P., et al.: J. Biol. Chem., 270, 6042 (1995), Campos, M., et al.: J. Immunol., 167, 416 (2001), Faundez, M., et al.: Antimicrob. Agents Chemother., 49, 126 (2005),
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