Catalogue Number:B387153
Chemical Name:Binucleine 2
Synonyms:N’-[1-(3-Chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl]-N,N-dimethylmethanimidamide;
CAS Number:220088-42-6
Molecular Formula:C₁₃H₁₁ClFN₅
Appearance:Light Yellow Solid
Melting Point:125-127°C
Molecular Weight:291.71
Storage:-20°C, Hygroscopic
Solubility:Chloroform (Slightly), DMSO (Slightly)
Stability
Moisture Sensitive
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Binucleine 2 is an inhibitor of cytokinesis function of the ARK-2 pathway. Highly isoform-specific inhibitor of Drosophila Aurora B kinase.
References:Smurnyy, Y., et al.: ACS Chem. Biol., 5, 1015-1020 (2010)
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