CAS:214697-26-4|5-(3-Bromophenyl)-7-[6-(4-morpholinyl)-3-pyridinyl]pyrido[2,3-d]pyrimidin-4-amine

Catalogue Number:B325700
Chemical Name:5-(3-Bromophenyl)-7-[6-(4-morpholinyl)-3-pyridinyl]pyrido[2,3-d]pyrimidin-4-amine
Synonyms:ABT 702; 5-(3-Bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2,3-d]pyrimidin-4-amine
CAS Number:214697-26-4
Molecular Formula:C₂₂H₁₉BrN₆O
Molecular Weight:463.33
Category:Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-(3-Bromophenyl)-7-[6-(4-morpholinyl)-3-pyridinyl]pyrido[2,3-d]pyrimidin-4-amine is an adenosine kinase (ADK) inhibitor and can be useful in attenuating myocardial ischaemia​/reperfusion injury and enhancing microvascular vasodilator function.
References:Wang, W., et al.: J. Cell. Mol. Med., 25, 2931 (2021); Davila, A., et al.: Microcirculation (Oxford, U. K.), 27, e12624 (2020)
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