CAS:208111-89-1|[3aR,4R(1E,3S),5R,6aS]-5-Benzoyloxy-4-(3-hydroxy-4-phenoxy-1-buten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one

Catalogue Number:B208380
Chemical Name:[3aR,4R(1E,3S),5R,6aS]-5-Benzoyloxy-4-(3-hydroxy-4-phenoxy-1-buten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one
Synonyms:(3aR,4R,5R,6aS)-5-(Benzoyloxy)-4-[(1E,3S)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]hexahydro-2H-cyclopenta[b]furan-2-one
CAS Number:208111-89-1
Molecular Formula:C₂₄H₂₃ClO₆
Molecular Weight:442.89
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:[3aR,4R(1E,3S),5R,6aS]-5-Benzoyloxy-4-(3-hydroxy-4-phenoxy-1-buten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one can be used as reagent/reactant in preparation of 15-Fluoro prostaglandin FP agonists as a new class of topical ocular hypotensives for the treatment of glaucoma. It can be obtained from (-)-Corey Lactone Benzoate (C694990) which a corey lactone derivative used in the preparation prostaglandin analogues for use as vasolidator as well as EP4 receptor agonists.
References:Andersen, N.H. et al.: Prostaglandins, 22, 809 (1981); Klimko, P., et al.: Bioorgan. Med. Chem., 12, 3451-3469 (2004); Ohta, C. et al.: J. Org. Chem., 74, 8298 (2009); Skuballa, W. et al.: Angew. Chem., 93, 1080 (1981);
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Taskcm is committed to providing cost-effective products that facilitate drug delivery with our customers.
Email:sales@ebclink.com