CAS:197142-34-0|(1R,3S,5R)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid

Catalogue Number:B201955
Chemical Name:(1R,3S,5R)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid
Synonyms:(1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid 2-tert-butyl Ester;
CAS Number:197142-34-0
Molecular Formula:C₁₁H₁₇NO₄
Appearance:White to Pale Yellow Solid
Melting Point:146 – 149°C
Molecular Weight:227.26
Storage:-20°C
Solubility:Acetone (Slightly, Sonicated), DMSO (Slightly, Sonicated), Methanol (Slightly, H
Stability
Hygroscopic
Category:Building Blocks; Miscellaneous;
Applications:1R,3S,5R)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid acts as a reagent in the preparation of fused bicycles end-capped with peptide derivatives as HCV inhibitors. Synthesis of (tert-butoxycarbonyl)azabicyclohexanecarboxylic acid via stereoselective cyclopropanation of pyrroline
References:Wang, G., et al.: Tetrahedron Lett., 54, 6722 (2013); Belema, M., et al.: From U.S. Pat. Appl. Publ. (2012), US 20120195857 A1 20120802
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