Catalogue Number:D245000
Chemical Name:Deoxynojirimycin
Synonyms:(2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol; 5-Amino-1,5-dideoxy-D-glucopyranose; Duvoglustat; Moranolin; Moranoline;DNJ
CAS Number:19130-96-2
Alternate CAS #
73285-50-4
Molecular Formula:C₆H₁₃NO₄
Appearance:White to Off-White Solid
Melting Point:195 – 196°C
Molecular Weight:163.17
Storage:-20°C
Solubility:Water (Slightly)
Stability
Hygroscopic
Category:Standards; Enzyme Activators and Inhibitors; Glycosidase Inhibitors;
Applications:Deoxynojirimycin inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancreatic alpha-amylase and amyloglucosidase.
References:Eur. J. Biochem., 142, 85-90 (1984), Crit. Rev. Biochem., 16, 21-48 (1984), Biochem. Biochem. Acta. , 825, 95 (1985), Suhm, K., et al.: J. Biol. Chem., 267, 21671 (1992)
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