CAS:189035-07-2|(11b,17b)-11-(1,3-Benzodioxol-5-yl)-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one

Catalogue Number:B198850
Chemical Name:(11b,17b)-11-(1,3-Benzodioxol-5-yl)-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one
Synonyms:Org 34517;
CAS Number:189035-07-2
Molecular Formula:C₂₈H₃₀O₄
Appearance:White to Off-White Solid
Melting Point:>211°C (dec.)
Molecular Weight:430.54
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Sparingly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(11b,17b)-11-(1,3-Benzodioxol-5-yl)-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one is a glucocorticoid receptor (GR) antagonists.
References:Verdouw, P. M., et al.: Pharmacol. Biochem. Behav., 154, 11-19 (2017); Reynolds, A. R., et al.: Drug Alcohol. Dep., 154, 100-104 (2015)
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