Catalogue Number:B326993
Chemical Name:Betamethasone 21-Mesylate (>90%)
Synonyms:(11β,16β)-9-Fluoro-11,17-dihydroxy-16-methyl-21-[(methylsulfonyl)oxy]pregna-1,4-diene-3,20-dione; 21-O-Mesylbetamethasone; Betamethasone 21-Methanesulfonate
CAS Number:1881-66-9
Molecular Formula:C₂₃H₃₁FO₇S
Appearance:White to Off-White Solid
Melting Point:>174°C (dec.)
Molecular Weight:470.55
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Betamethasone 21-Mesylate is an intermediate in synthesizing Doxybetasol (Betamethasone Valerate EP Impurity B) (D561000), which is an impurity of Betamethasone (B327000). It is a glucocorticoid used as an anti-inflammatory agent.
References:Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005); Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006)
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