Catalogue Number:A480998
Chemical Name:D-Alanine-3,3,3-d3
CAS Number:177614-69-6
Alternate CAS #
338-69-2
Molecular Formula:C₃H₄D₃NO₂
Appearance:White to Off-White Solid
Melting Point:>243°C (dec.)
Molecular Weight:92.11
Storage:4°C
Solubility:Aqueous Acid (Slightly), Aqueous Base (Slightly), Water (Sparingly, Sonicated)
Stability
Stable under recommended storage conditions., Stable Under Recommended Storage C
Category:Building Blocks; Isotopic Labeled Analogues;
Applications:D-Alanine-3,3,3-d3 is a labelled form of D-Alanine (A480995) which is an amino acid that is commonly found in bacteria, such as Streptococcus faecalis. It is essential for the biosynthesis of peptidoglycan crosslinking sub-units that are used for bacterial cell walls. D-Alanine is also known to cause cytotoxic oxidative stress in brain tumour cells.
References:Ellsworth, B., et al.: Chem. Biol., 3, 37 (1996); Ferrari, E. et al.: Nat. Biotech., 3, 1003 (1985); Stegman, L., et al.: Human Gene Ther., 9, 185 (1998); Wood, W. & Gunsalus, I.: J. Biol. Chem., 190, 403 (1951)
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